Microlex® CMC L, M, and H types

Microlex® provides pharmaceutical carboxymethylcelluloses under the trade names Microlex CMC L, M, and H types, Microlex® carboxymethylcellulose (CMC) is made by reacting sodium monochloroacetate with alkalicellulose under rigidly controlled conditions. The resultant anionic polymer is purified and dried.

L-type provides smooth solutions, based on uniform substitution with low viscosity.

M-type provides solubility and viscosity stability on medium viscosity.

H-type provides solubility and viscosity stability on strong high viscosity. Microlex CMC grades designated L, M, and H are compliant with the monograph requirements of the EP, USP/NF and Japanese Pharmacopoeia.


Microlex® MCC 101 & 102 types

Microlex® MCC provides pharmaceutical microcrystalline cellulose 101 and 102  grades  primarily  intended  for  wet

granulation and direct compression applications respectively.

Microlex® MCC 101 is a fine particle size material. When used at about 20% in a wet granulation formulation it confers a range of benefits. The granulation becomes “robust” as the Microlex® MCC allows superior distribution of the water through the granulation. This promotes even granule growth and light granules for easy fluidization. Tablets made from these granules are typically easily disintegrated using conventional superdisintegrants even when hard tablets are compressed.

In direct compression Microlex® MCC 102 is a highly compactable material.The plastic defamation characteristics of  MCC 102

type mean that very hard tablets can be produced at light compaction forces, extending tooling lifetime and solving problems with poorly compressible actives. In high dose direct compression applications, Microlex® MCC 102 should be included in your formulation trials.


Copyright © 2013 Microlex e.U. All rights reserved. Copyright/IP Policy Company