Liquid dosage forms

This range of excipients is composed of monoesters and triesters of fatty acids like lauric, stearate and oleic which differ in terms of their hydrophilic/lipophilic balance value and are used to form water-in-oil or oil-in-water emulsions, also may be used alone as lipophilic emulsifiers to formulate water-in-oil emulsions. This range may be used practically in all emulsion formulations, in particular in pharmaceutical products such as: creams, ointments, lotions, syrups, solutions, liquid ampoules, dispersions, semi-solids, softgels. Sorbitan esters and their ethoxylates are a range of mild nonionic surfactants with multifunctional benefits in a number of healthcare applications. Entirely vegetable-derived have long-standing pharmacopoeia approvals and are ideal in topical preparations.

Functional benefits

- Nonionic emulsifiers

- Excipients

- Dispersants

- Solubilisers

- Very low peroxide value

- Low moisture content

- Pyrogen-free sorbitol starting material

- Packaged under nitrogen

Sorbitan Esters
Trade Name	INCI Name	Pharmacopoeia Monograph
Microlex® SE 20	Sorbitan Laurate	BP, PhEur
Microlex® SE 40	Sorbitan Palmitate	----,----
Microlex® SE 60	Sorbitan Stearate	BP, PhEur
Microlex® SE 65	Sorbitan Tristearate	BP, PhEur, USP/NF
Microlex® SE 70	Sorbitan Isostearate	----,----
Microlex® SE 80	Sorbitan Oleate	BP, PhEur, USP/NF
Microlex® SE 83	Sorbitan Sesquioleate	BP, PhEur, USP/NF
Microlex® SE 85	Sorbitan Trioleate	BP, PhEur, USP/NF
Ethoxylated Sorbitan Esters
Trade Name	INCI Name	PharmacopoeiaMonograph
Microlex® PSE 20	Polyoxyethylene sorbitan monolaurate	BP, PhEur, USP/NF
Microlex® PSE 40	Polyoxyethylene sorbitan monopalmitate	BP, PhEur, USP/NF
Microlex® PSE 60	Polyoxyethylene sorbitan monostearate	BP, PhEur, USP/NF
Microlex® PSE 80	Polyoxyethylene sorbitan monooleate	BP, PhEur, USP/NF

. Suppository base hard fats

. Microlex® HF

. Description

HF W35 hard fat suppository base with a high mono- and diglyceride content. High elasticity and polarity. Hydroxyl value of 40-50 mg KOH/g, saponification value of 230-240 mg KOH/g.

. Description

HF H15 hard fat suppository base with a low content of mono- and diglycerides. Hydroxyl value of 5-15 mg KOH/g, saponification value of 230-240 mg KOH/g.

. Functions

.Stiffening agent

.Suppository base

Suppository base Hard Fats
Trade Name	INCI Name	Pharmacopoeia Monograph
Microlex® HF W35P	Glycerides, C12-C18	PhEur, USP/NF
Microlex® HF W35	Glycerides, C12-C18	PhEur, USP/NF
Microlex® HF H15P	Glycerides, C12-C18	PhEur, USP/NF
Microlex® HF H15	Glycerides, C12-C18	PhEur, USP/NF